Observation Study to Evaluate the Efficacy and Safety of Ifosfamide/Mesna in Patients With Metastatic Castration-resistant Prostate Cancer

Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Observational
SUMMARY

Prostate cancer is the 2nd most common cancer in men worldwide. Based on the results of several recent clinical trials, systemic treatments including hormone inhibitors, docetaxel, cabazitaxel, and PARP inhibitors are being used as standard treatment for patients with metastatic castration-resistant prostate cancer. However, there is insufficient research on salvage therapy for patients with metastatic castration-resistant prostate cancer who have failed standard treatment. In this study, the investigators will evaluate the effectiveness and safety of ifosfamide in castration-resistant prostate cancer by analyzing the treatment outcomes of patients who received ifosfamide/mesna treatment as salvage therapy.

Eligibility
Participation Requirements
Sex: Male
Minimum Age: 19
Healthy Volunteers: f
View:

• 19 years and older adult male

• Patients with histologically confirmed prostate cancer

• Castration-resistant prostate cancer

• ECOG 2 or less

• Patients with previous docetaxel exposure

• Patients with available PSA level

• Patients with evaluable disease based on RECIST 1.1

Locations
Other Locations
Republic of Korea
Division of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, Republic of Korea
RECRUITING
Seoul
Contact Information
Primary
Sang Joon Shin
inspector@yuhs.ac
82-2-2228-8130
Time Frame
Start Date: 2016-11
Estimated Completion Date: 2026-11
Participants
Target number of participants: 60
Treatments
Castration-resistant prostate cancer patients treated with ifosfamide/mesna
Related Therapeutic Areas
Sponsors
Leads: Yonsei University

This content was sourced from clinicaltrials.gov